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Was Inventor of the MRI denied Nobel Because of Creationism Beliefs?

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  • Was Inventor of the MRI denied Nobel Because of Creationism Beliefs?

    War book: Damadian Nobel Prize 7/15/2004 SH BT CL

    Was the Inventor of Magnetic Resonance Imaging not Awarded the Nobel
    Prize Because of His Creationism Beliefs?

    Jerry Bergman Ph.D.


    Introduction

    Can a personas beliefs about the role of an intelligent creator in
    creating life prevent an otherwise deserving scientist from being
    awarded a Nobel Prize? One of the most blatant cases occurred
    recently with the awarding of the Nobel Prize in Medicine for the
    discovery of magnetic resonance imaging. Instead of awarding the
    prize to the actual inventor, Dr. Raymond Damadian, it was given to
    Paul C. Lauterbur of the University of Illinois and Sir Peter
    Mansfield of the University of Nottingham, England.

    The invention of MRI was no small achievement. MRI technology is now
    over a five-billion-dollar-per-year industry, and is the premiere
    medical diagnostic imaging method available today. It is, in general,
    able to image diseased tissue more accurately, more safely, and more
    efficiently than any other medical imaging technique. Although x-ray
    and computed tomography are still often used, a major reason is
    because of their lower cost. So far, over a half-billion MRI scans
    have been done since its invention.



    The Inventor

    Raymond Damadian was born in Manhattan on March 16, 1936. When
    Damadian was ten years old, his grandmother died of breast cancer.
    She had been in great pain, and seeing that made a lasting impression
    on young Raymond. Her illness was especially hard on Raymond because
    he was very close to his grandmother (Mattson and Simon, 1969,
    p. 615). This event set Damadian on a course to find a way to help
    treat cancer. He first got the idea for MRI while working with
    nuclear magnetic resonance (NMR), scanning a type of Dead Sea bacteria
    called halophiles that had twenty times the potassium level compared
    to most other bacteria (1994, p. 55). The research with the bacteria
    worked so well that Damadian then recognized that detecting tissue
    abnormalities in humans was possible. As chronicled in the book A
    Machine Called Indomitable, Damadian spent most of the rest of his
    career developing MRI.

    In 1969, he was the first to publish an article proposing the use of
    magnetic resonance to scan human bodies for signs of disease (Mattson
    and Simon, 1996, Appendix and Chapter 8). In 1970, he found a major
    difference in the MR signals between various tissue types, a discovery
    that made the MRI scanner possible. He also discovered the difference
    between T1 and T2 relaxation times that allow scanning of body tissues
    with enough clarity to enable MRI technology to be used for numerous
    practical medical applications (Kevles, 1997). In March of 1971, his
    results were published in the journal Science. As a review of the
    case in Science concluded, ÒDamadian published the first paper that
    used MRI to distinguish between healthy and cancerous tissueÓ (Vogel,
    2003, p. 382). DamadianÕs work was also becoming widely known: as
    early as 1973, articles were appearing in popular magazines about his
    work (Edelson, 1973, p. 99).

    After he published his Science article, Damadian continued to improve
    MRI technology. In the spring of 1971, he proposed the MR focus spot
    scanning method. In March of 1972, Damadian filed for a patent for
    his MR scanner based on his T1 and T2 discovery. In 1977, Damadian
    and his graduate students, Michael Goldsmith and Larry Minkoff, built
    the first MR scanner, which they named Indomitable. In the same year,
    on July 3, they produced the first MRI human body scan. In 1980,
    Dr. Damadian introduced the first commercial MRI scanner, which was
    built by Fonar Corporation of New York, a company that he founded
    (Damadian, 1994, p. 93). In 1983, Damadian introduced the Beta 3000,
    a machine that Òcreated quite a stir,Ó and drew good responses from
    Òdoctors who examined the imagesÓ (Kleinfield, 1985, p. 217).

    Soon, several other companies also began building MRI scanners,
    forcing Damadian to appeal to the courts to protect his patents.
    DamadianÕs concern about how easily someoneÕs patent rights can be
    infringed upon (and the harm this problem causes America and our
    economy) was detailed in a Saturday Evening Post article that he wrote
    (1994, p. 58+). He continued fighting for his patent rights and,
    finally, in 1997, the U.S. Supreme Court enforced DamadianÕs 1972
    patent, affirming his priority over Lauterbur, and asserting that all
    MRI scanners that use DamadianÕs T1 and T2 method to create MRI images
    are DamadianÕs property. All of his lawsuits took a full fifteen
    years to resolveÑthe first lawsuit in the case was filed in 1982
    against Johnson and Johnson (Damadian, 1994, p. 101). The Supreme
    Court actually made a special ruling in DamadianÕs case, creating a
    whole new category that gave his 1972 patent both validity and
    protection.

    The damage award from General Electric alone was a 128.7 million
    dollars (Siemens, Hitachi, Philips, Shimadzu, and Toshiba all settled
    out of court for undisclosed amounts). Damadian poured this money
    back into research and development in order to further improve MRI
    technology, developing both oblique imaging and multiangle oblique
    imaging. He also pioneered what is now called the open MRI, which
    does not require the patient to lie in a small confining tube but on a
    large open platform. He now manufactures the only open standup MRI on
    the market today that allows imaging while the patent is in a vertical
    position. Among the many other innovations his company developed are
    small, lighter weight, portable MRIÕs, and MRIs that can be safely
    used in operating rooms.

    In 1988, President Ronald Reagan awarded the National Medal of
    Technology jointly to Damadian and Lauterbur for their magnetic
    resonance technology contributions. In 1989, Damadian was inducted
    into the National Inventors Hall of Fame of the U.S. Patent Office.
    The first MRI scanner ever builtÑDamadianÕsÑwas placed in the
    Smithsonian Institution in the same year. Damadian was also awarded
    the seventh annual Lemelson-MIT Lifetime Achievement Award (worth half
    a million dollars) on April 25, 2002, for pioneering magnetic
    resonance scanning technology. Damadian was later awarded the coveted
    Lincoln-Edison medal for his pioneering work in inventing the MRI. In
    March of 2004, he was awarded the quarter-million-dollar Franklin
    Institute Medal Òfor building the first MRI scannerÓ and for
    Òachieving the first commercial machine in 1980.Ó

    The record of DamadianÕs achievements, and his priority, are well
    documented and supported by these awards, plus his many patents and
    dated, refereed publications. Damadian clearly originated the MRI
    concept, and Lauterbur even cited DamadianÕs 1971 Science paper in his
    notebook, although he did not cite Damadian in his March 1973 Nature
    paper, claiming lack of room. Mansfield and his co-authorsÕ work,
    which further improved on DamadianÕs and LauterburÕs work, was not
    published until 1974.

    Furthermore, DamadianÕs contributions in the commercial development of
    the MRI machine are also widely recognized. Kean and Smith, in their
    standard history of MRI text, note that the two factors that were
    primarily responsible for the decision of various research centers and
    commercial investments to investigate developing a technique of NMR
    imaging in vivo were, first, the work of Damadian and, second, the
    impact of CT on medical imaging (1986, p. 1). Lauterbur is mentioned
    later, and only then as the originator of the term zeugmatography for
    MRI (a term that never caught on!). This definitive history of MRI
    concluded:

    When a well-known company advertises ÒWe bring good things to lifeÓ
    and shows a patient being scanned with MRI, television viewers might
    think that magnetic resonance scanning was invented and brought to
    market through the efforts of a large team of corporate scientists....
    In reality, MR scanning was invented, patented and brought to market
    largely through the efforts of one man, a medical doctor, Raymond
    V. Damadian, who was assisted along the way by others who believed in
    him and his dream. Instead of a deep-pocketed corporate R&D budget,
    he had only his salary as a professor and just enough funding
    scrounged up from here and there to pay the salaries of his two
    graduate assistants and to buy the second-hand components and the
    liquid helium used for constructing and cooling his first scanner.
    ...The academic laboratory in Brooklyn in which the machine was built,
    personally gerrymandered with jackhammer and sledgehammer by Damadian
    and his associates from quarters once relegated to laboratory rats,
    possessed the qualities of a machine shop more than a university
    medical lab (1996, p. 611).



    The MRI invention was more difficult than it first may appear, because
    many of the experts firmly believed that building a magnet large and
    powerful enough to image humans was impossible (Kevles, 1997, p. 178).
    Scanners today use magnetic fields as much as 80,000 times stronger
    than the EarthÕs background magnetic field. A common concern by
    researchers was that the MRI magnetic field would affect materials in
    the body that are attracted to a magnet, such as iron, which is part
    of hemoglobin, ferritin (iron oxide), and other biological
    structures. Extensive research has proven this fear unfounded.



    Support from Others

    Many scientists who had worked with Damadian were upset at the Nobel
    committeeÕs slight. One, Dr. Eugene Feigelson, Dean of the State
    University New York College of Medicine on Long Island where Damadian
    was on the staff, stated Òall of MRI rests on the fundamental work of
    Dr. DamadianÓ (quoted in Reuters newsletter). Dr. Feigelson added,
    Òwe are perplexed, disappointed and angry about the incomprehensible
    exclusionÓ of Dr. Damadian from the Nobel (Montgomery, 2003). Kevles,
    in a study of MRI, concluded

    in the summer of 1977Ñin the footsteps of Edison rather than
    RoentgenÑDamadian preempted his scientific competitors. He called a
    press conference to introduce and demonstrate a whole-body NMR imaging
    machine which he called the ÒIndomitable.Ó Whether or not there really
    were contenders for this particular prize at this particular time is
    open to discussion. What is not debated is the fact that Damadian,
    with his vision of a body-size NMR machine, leaped from using magnets
    only large enough to examine tissue specimens in test tubes to
    building his own superconducting magnet with a bore (or opening) large
    enough to encircle a grown human being. No one else had the
    imagination, or hubris, to skip the in-between steps undertaken by
    othersÑexamining first small mammals and then parts of the human
    bodyÑand jump to the construction of a whole-body machine (1997,
    p. 179).



    Florida State University professor Michael Ruse concluded that
    Damadian was excluded from the Nobel even though

    he was the inventor of the first machine that discovers cancers
    through magnetic resonance imaging, [rather] the award went to two
    other and somewhat subsequent scientists, Paul Lauterbur and Peter
    Mansfield. Notoriously, the Nobel committees never reveal their
    deliberations (until everyone is long dead) and never change their
    minds (2004).



    The Claims

    Why was Damadian excluded from the Nobel for his many critical
    contributions to MRI technology? A common claim by the researchers in
    this area is that DamadianÕs technique by itself was not feasible to
    produce viable, commercial, economical scanners. It is correctly
    noted that DamadianÕs scan took four hours and forty-five minutes to
    complete 106 data points, and its resolution was not of the quality
    that enabled his system to be used as a practical scanner for pictures
    (although he realized that one did not need pictures to diagnose
    disease, but this could be done with data points). Lauterbur, after
    seeing DamadianÕs results, came up with the idea now known as
    one-dimensional imaging involving algebraic and computer algorithm
    reconstruction to produce pictures (Hollis, 1987). Lauterbur
    eventually submitted his idea to Nature, which rejected the paper
    (Kevles, 1997, p. 181). He then revised the paper and resubmitted it.
    This time Nature accepted the paper, and it was published in 1973, the
    same year that Sir Peter Mansfield published his first paper on his
    MRI imaging technique idea.

    MansfieldÕs idea was very similar to LauterburÕs, only he described
    his idea in terms of the physics of solids rather than liquids, as did
    Lauterbur. LauterburÕs and, to a lesser extent, MansfieldÕs, work
    produced sufficient improvement to achieve the goal of a viable MRI
    scanner for medical diagnosis. Mansfield may have produced the first
    MRI image of a live human body using LauterburÕs technique, but not
    the first MRI image (Hollis, 1987, pp. 96-97). Damadian had made at
    least six previous MRI images of cancer patients. All these facts are
    not questioned.

    The concern of DamadianÕs supporters is not that Mansfield and,
    especially, Lauterbur did not deserve the award, but that Damadian did
    the pioneering work and made many of the critical initial discoveries.
    Lauterbur and Mansfield only improved upon his discoveries.
    Specifically, Lauterbur discovered how radiation in an applied
    magnetic field could be used to produce two-dimensional images.
    Mansfield showed how the magnetic gradients could be mathematically
    analyzed to improve both the speed and the efficiency of the image
    generation process, allowing the unit to be even more practicable.

    Dr. Damadian first conceived of using T1 and T2 measurements to scan
    the body, and today more than ninety-five percent of all MRI scans use
    T1 and T2 measurements (Stracher, 2002, p. 2). Furthermore, the will
    of Alfred Nobel states that the prize in medicine is to be awarded to
    the person that has Òmade the most important discovery within the
    realm of physiology or medicineÓ and not for techniques or inventions
    that exploit that discovery, such as the work of Lauterbur and
    Mansfield (Fant, 1991, p. 329). The award guidelines for medicine are
    different then the chemistry and physics award criteria, which do
    allow an award to be given for developing techniques that improve a
    previous discovery.



    Comparisons with the Wright Brothers

    A parallel with the invention of the airplane is critical to
    illustrate DamadianÕs case. The Wright brothers achieved the specific
    discoveries that made the first heavier-than-air manned flight
    possible, but their crude, rickety contraption was totally
    impractical. For example, the Wright brothersÕ first successful plane
    flight on December 17, 1903, required the pilot to recline on a wood
    frame covered with paper and cloth, and used skis to land. The craft
    flew only 852 feet, and was in the air for only twelve seconds. The
    Wrights operated their plane using wing-warping controls rigged to
    their hips (Scheider, 2003, p. 502). Furthermore, numerous aspects of
    the Wright brothersÕ design had to be modified. For example, the tail
    had to be placed near the rear rather than on the front, as it was in
    the Wright brothersÕ plane, before manned flight was practical (Jakob,
    1990).

    Many important improvements to the plane were made by others, such as
    Glenn Curtiss, who invented the hinged aileron (a development that
    even the Wright brothersÕ planes later used) (Combs, 1979).
    Nonetheless, no one today claims that Curtiss invented the airplane,
    even though his invention is the basis of modern aviationÑcredit is
    rightfully given to the Wright brothers because they were the ones who
    first made the critical developments that made flight possible,
    especially the wing design that created liftÑand they were the first
    humans to fly in a heavier-than-air craft (Jakob, 1990). The specific
    landmark steps in MRI technology made by Damadian are as follows:

    1) his scientific research and theory of the cell that led him to
    consider NMR as a method for detecting cancer;

    2) his discovery of the cancer NMR scanning signal in animal tissue
    together with the demonstration of the diversity of NMR relaxation
    times among healthy tissues;

    3) his building of a superconducting magnet (all of his competition
    were experimenting

    with permanent magnets);

    4) his filing of the original (and the foremost) patent on NMR
    scanning;

    5) his achievement of the first whole-body NMR scan of a human and the
    resultant image;

    6) his development of the worldÕs first commercial NMR scanners
    (Mattson and Simon, 1996, p. 613).

    DamadianÕs first MRI machine used a point-by-point analysis, a very
    impractical approach for scanning. Nonetheless, as noted above, his
    T1 and T2 observation Òwas an Eureka moment for Paul Lauterbur. After
    seeing Dr. DamadianÕs experiment repeated by a graduate student,
    Mr. Lauterbur dined at a hamburger joint, where he . . . realized he
    could subject the nuclei to a second magnetic field that varied in
    strength in a precise wayÓ (Stacher, 2003, p. 2). Lauterbur then
    realized that he could use this technique to construct an image, a
    conclusion that he recorded in a notebook and had witnessed the next
    day. As Stracher notes, ÒOver the years, Mr. Lauterbur has been less
    than forthcoming about giving Dr. Damadian credit. In his notebook he
    acknowledged Dr. DamadianÕs 1971 paper, but his subsequent articles
    didnÕt mention it. Mr. Lauterbur explains that by the time he
    published his first paper, another group had made measurements on a
    tumor in a mouseÕs tail. ÒI needed to keep the list of references to
    very few, so I used Ôthe later oneÕÓ (2003, p. 2). Others have
    observed that LauterburÕs achievement, in essence, involved taking the
    signals and drawing them on a piece of paper quickly and
    efficientlyÑclearly a major improvement, but hardly the initial
    discovery.

    The fact is, Damadian is the pioneer of MRI, has the first patents,
    and built the first MRI scanner; conversely, Lauterbur only augmented
    DamadianÕs accomplished work. Although Lauterbur succeeded in getting
    a much better MRI image, Damadian built the first workable unit;
    Lauterbur only refined the technique. This is like crediting Curtis
    for inventing the airplane, and snubbing the Wright brothers.
    Although LauterburÕs technique is used with DamadianÕs equipment
    today, just as all modern planes use CurtisÕs improvements, this
    should not detract from the WrightsÕ, nor DamadianÕs, original
    developments.

    Philip Yam (2003, p. 42), noted that controversies about the Nobel
    Prize award are not uncommon, but that Òthe Nobel committeeÕs decision
    in this case, however, seemed to be an intentional slap in DamadianÕs
    face. Award rules permit up to three winners in each category, so the
    committee could have included Damadian. Curiously, the NobelÕs press
    release describing the winners typically acknowledge other
    contributors, but failed to mention Damadian.Ó In most articles about
    the award, Damadian was totally ignored (e.g. The Fort Wayne, Indiana
    Journal Gazette ÒMRI Pioneers Win Nobel PrizeÓ Tuesday, October 7,
    2003, p. 3a).



    The Background of DamadianÕs Work

    DamadianÕs education is important in understanding his contributions.
    He was studying violin at the world famous Juilliard School of Music
    when he triumphed over 10,000 other applicants and was awarded a Ford
    Foundation Scholarship at age fifteen, enabling him to go to the
    University of Wisconsin to complete a degree in math, and then on to
    the Albert Einstein School of Medicine where he earned his M.D. He
    later completed graduate work in biophysics at Harvard University.
    His interest was not in clinical practice, but in research and
    development. As noted above, he first became interested in medicine
    at the age of ten after witnessing the pain and suffering that
    resulted from his grandmotherÕs cancer. He wished to create new
    methods that would aid in diagnosing disease at an earlier stageÑwhen
    it was still treatable (Mattson and Simon, 1996, p. 623).



    The Patents

    In a review of the MRI patents, I found Lauterbur had only four that
    related to MRI; Peter Mansfield had a total of seventeen; and Damadian
    a total of sixty-oneÑincluding many of the most important patents, for
    MRI apparatus. No MRI unit can be manufactured today without
    reference to DamadianÕs patents.

    In spite of his incontestable patents, Damadian faced a long struggle
    to vindicate his patent claims. A 1982 jury trial found DamadianÕs
    MRI patent valid and infringed upon by his competitors. Yet, six
    weeks after the trial, the judge voided the juryÕs verdict and
    substituted his own verdict, even though DamadianÕs company had spent
    2.2 million dollars in legal fees during the lawsuit. Damadian
    appealed the decision and eventually prevailed in the highest court of
    the land in October 1997. The Wright brothers also spent years in
    court defending their claims, and they too were finally vindicated by
    the Supreme Court .



    DamadianÕs Religious Beliefs Central to the Case

    Damadian became a born again Christian in 1957 at a Billy Graham
    Crusade in Madison Square Garden, New York (Chuvala, 1996). Extensive
    reading and study on science and theology since then has put his faith
    on firm footing, especially on the creation/evolution question.
    Furthermore, he has been active in this controversyÑe.g. HeibertÕs
    article ÒDarwin Wins Friends in RomeÓ in British Columbia Report dated
    Nov. 11, 1996, pp. 30-31.

    Numerous articles have commented that DamadianÕs religious beliefs
    were central to why he was denied the Nobel award. For example, a
    Christianity Today article suggested that the reason for the Nobel
    Prize CommitteeÕs snubbing Damadian was because he is a devout
    Christian and a creationist. In an excellent article about the Nobel
    Prize and Damadian in Scientific American, Yam (2003, p. 42) asked,
    Ò... did his creationist viewpoint play a role? He is on the
    technical advisory board of the Institute for Creation Research.Ó
    Damadian is also on the reference board for Answers in Genesis
    Creation Museum. Furthermore, Damadian is Òidentified by many
    websites as a prominent creation scientistÓ and, according to Olsen,
    Òmost scientists are not creationists and [they] tend to look askance
    at scientists who believe that wayÓ (2003). Vision magazineÕs Ronald
    Bailey added that the Nobel committee could have been Òswayed by the
    fact that Damadian, although a brilliant inventor, is apparently a
    creation science nut. In ironic contrast, LauterburÕs current
    research is on the chemical origins of lifeÓ (quoted in Olsen, 2003).

    Colleagues had mentioned to Damadian many years ago that his stand on
    creationism may create problems for him in earning a Nobel Prize
    because of the scientific establishmentÕs clear bias against this
    worldview (Richards, 2003, p. 1). Ruse concluded that perhaps
    Dr. Damadian does have good reasons to believe that he was passed over
    due to his beliefs. Ruse wrote that Damadian

    is not just an inventor, but also a very prominent Christian. And not
    just a Christian of any bland kind, but a Creation ScientistÑone of
    those people who believes that the Bible, especially including
    Genesis, is absolutely literally trueÑsix days of creation, Adam and
    Eve the first humans, universal flood, and all of the rest. It is at
    least as likely a hypothesis that Damadian was ignored by the Nobel
    committee because they did not want to award a Prize to an American
    fundamentalist Christian as that they did not think his work merited
    the fullest accolade. In the eyes of rational EuropeansÑand Swedes are
    nothing if not rational EuropeansÑit is bad enough that such people
    exist, let alone give them added status and a pedestal from which to
    preach their silly ideas. Especially a scientific pedestal from which
    to preach their silly anti-science ideas. Is this unfair? One
    certainly feels a certain sympathy for the Nobel committee. Creation
    science is wrong and (if taught to young people as the truth)
    dangerous. It does represent everything against which good science
    stands (2004).



    Ruse added that DamadianÕs situation should be looked at from an
    historical perspective. For example, he notes that even the most well
    respected scientists have believed in

    some very strange things, and if we start judging one area of their
    work in terms of other beliefs that they have, we could well do more
    harm than good. Isaac Newton, the greatest scientist of them all, had
    some very strange views about the proper interpretation of such
    Biblical books as Daniel and Revelation, and in respects believed
    things about the universeÑits past and its futureÑthat make today's
    Creation Scientists seem comparatively mild. More recently, Alfred
    Russel Wallace, the co-discoverer of natural selection along with
    Charles Darwin, became an enthusiast for spiritualism, believing that
    there are hidden forces controlling every aspect of life. People knew
    this and were embarrassed by it, but it did not stop them from
    celebrating and praising Wallace's great scientific work. He was made
    a Fellow of the Royal Society, and given Britain's greatest award for
    achievement, the Order of Merit (2004).



    Ruse is not saying this because he a creationist sympathizer. He
    notes that all of his life he has

    fought for evolution and against CreationismÑin writings, on the
    podium, and in court in 1981 as a witness in Arkansas against a law
    demanding that Creation Science be taught alongside evolution in the
    state supported schools. But as one who loves science above all and
    thinks it the greatest triumph of the human spiritÑas one who has no
    religious beliefs whatsoeverÑI cringe at the thought that Raymond
    Damadian was refused his just honor because of his religious
    beliefs. Having silly ideas in one field is no good reason to deny
    merit for great ideas in another field. Apart from the fact that this
    time the Creation Scientists will think that there is good reason to
    think that they are the objects of unfair treatment at the hands of
    the scientific community (2004).



    DamadianÕs position on certain issues also contradicts the direction
    that many people are trying to take our country, e.g., Creation Ex
    nihilo 16(3):35-37, June-August 1994, ÒSuper-scientist slams societyÕs
    spiritual sicknessÓ). Damadian has often spoken openly about his
    religious beliefs. For example, he did a seminar at Pittsberg State
    University at Pittsberg, New York, in October of 2000 on creation
    science (Richards, 2003).

    No doubt the Nobel Prize committee felt that awarding Damadian the
    Nobel Prize would legitimize his creation views, the same reason why
    well known science writter Forrest Mims was fired as a scientific
    writer for Scientific American. They told him as a writer for one of
    AmericaÕs top science magazines he would give credibility to creation,
    and for this reason only he was fired. Wilder-Smith documented
    another case similar to DamadianÕs:

    the situation is such today that any scientist expressing doubts about
    evolutionary theory is rapidly silenced. Sir Fred Hoyle, the famous
    astronomer, was well on his way to being nominated for the Nobel
    Prize. However, after the appearance of his books expressing
    mathematically based doubts as to Darwinism, he was rapidly
    eliminated. His books were negatively reviewed and no more was heard
    about his Nobel Prize (1987, p. iii).





    Reasons Offered Not to Award Damadian

    Some people believe that Damadian was not awarded the prize because he
    choose to leave academia and pursue research at his own company. This
    reasoning is hardly valid because many academics have left the Ivy
    Tower to continue their research elsewhere. Some, such as William
    Shockley, the inventor of the transistor, and the Wright brothers,
    even founded companies that allowed them to profit from their
    discoveries.

    Others claim DamdianÕs denial was due to resentment because he
    defended his patent rights in court. Damadian is often characterized
    as rash and litigious for pursuing the court cases to save his company
    (Stracher, 2002, p. 2). Although a number of individuals in the MRI
    community have criticized him for doing this, Damadian had no choice
    because fighting for his patent rights was a matter of his companyÕs
    survival. It is very common for inventors to be forced to defend
    their patents in courtÑEdison, Bell, Marconi, and Philo Farnsworth,
    the inventor of the TV, all had to do so.

    Likewise, the Wright brothers had no choice but to defend their
    patents and spent many years in court, including five years in
    litigation with Herring-Curtiss Company. The court also eventually
    vindicated the Wrights, and ruled that they held the Òpioneer patentÓ
    on manned flight (Combs, 1979, p. 357). The Wrights engaged in a
    dozen lawsuits in three nations. Of those cases that went to court,
    the Wrights won every one, as did Damadian (Combs, 1979, p. 357). One
    difference in the WrightsÕ and DamadianÕs case is that the Smithsonian
    spent almost forty years trying to discredit the Wright brothers, but
    has formally acknowledged Damadian as the inventor of MRI.

    Many competitors have unscrupulously attacked DamadianÕs personality,
    claiming that his ÒegotismÓ and ÒmegalomaniaÓ was the issue. This is
    name calling, and it is not rare to accuse potential Nobel laureates
    of this fault. Another claim is that Damadian once walked out of a
    professional meeting. This is hardly a reason to deny the award. No
    indication was given as to why he walked out. Perhaps he went the
    bathroom, had a late appointment, or did not feel well. According to
    my experience and the persons I interviewed (such as Roger Richards),
    Damadian is a hardworking, devoted Christian. Richards said he is
    Òone of the most inspiring, humble, and intelligent menÓ he has ever
    met, and furthermore, he is a very generous man. For example,
    Damadian Òrefused to accept any compensation for coming to speak at a
    seminar Richards gave, and stayed for hours afterward answering
    studentÕs questions. . .Ó (2003, p. 1). Richards adds (p. 3) that
    Damadian is also a Òwitty and pleasant individual who is not one to
    put on airs.Ó Even if Damadian were egotistical and had some
    personality quirks, these are not valid reasons to deny him a Nobel
    Prize. Kary Mullis, the inventor of PCR, clearly had some personality
    issues, yet was given the award

    Kary Mullis is not likely to fit most peopleÕs profile of a serious
    scientist. He is a man who quit the lab to work in a restaurant, a
    man who had a midnight brawl on a beach with a fellow researcher, a
    man who elicits both giggles and awe from other scientists. Yet
    Mullis, 48, ... is responsible for what many consider the most
    important advance in genetic research since the discovery of DNAÕs
    double helix ... his inventionÑthe polymerase chain reaction, or
    PCRÑhas revolutionized microbiology, medical diagnostics, criminal
    investigation, even evolution (Dwyer, 1993, p. 8).



    Mullis also

    speaks with some bitterness about the years that followed his
    discovery. He was turned down flat by prestigious journals when he
    tried to publish his findings. He remembers the reception to his idea
    by colleagues at Cetus as ice cold. Then, he maintains, as PCR was
    taking off, they sought to attach themselves to its development (1993,
    p. 10).



    Nor is Damadian the only controversial case when it comes to the
    awarding of a Nobel Prize. Jonas Salk, the inventor of the Salk polio
    vaccine, was not awarded the prize, although Dr. Enders was (in 1954).
    Frederick Banting and his boss J.J.R. McCleod (who was on vacation at
    the time) were awarded the Nobel, and Charles Best (who, as is well
    documented, actually discovered the use of insulin treatment for
    diabetes), was not.

    The attacks against Damadian began long before he was successful.
    McAuliffe wrote:

    When Dr. Raymond Damadian proposed in 1971 that body images more vivid
    than X-rays could be produced with a machine that measures magnetic
    properties of atoms, he was considered crazy. Critics called his
    theory, which built upon a phenomenon known as nuclear magnetic
    resonance, Òvisionary nonsense.Ó Prestigious scientific journals
    refused to publish his findings, and government funding bodies refused
    to support his research.... This rigorous early training promoted his
    mastery of science. Nothing, however, could prepare Damadian for the
    hostility with which his colleagues greeted his ideas. ÒI believe the
    source of their anger,Ó says Damadian, Òwas that my findings
    overturned theories upon which literally thousands of scientists had
    pinned their reputations (1987, p. 66).



    Conclusion

    In conclusion, a strong case can be made that DamadianÕs beliefs about
    origins was the reason for his not receiving the award, and that he is
    the legal and rightful inventor of the MRI machine. Consequently he
    rightfully should have received the award.



    Acknowledgments: I would like to thank Shelley Hausch and Bert
    Thompson, Ph.D. for their critical review of an earlier version of
    this manuscript.



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