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STUDIES FROM D.B. SAAKIAN AND COLLEAGUES YIELD NEW INFORMATION ABOUT PHYSICS
Science Letter
June 16, 2009
According to a study from Yerevan, Armenia, "Using methods of
statistical physics, we present rigorous theoretical calculations
of Eigen's quasispecies theory with the truncated fitness landscape
which dramatically limits the available sequence space of information
carriers. As the mutation rate is increased from small values to large
values, one can observe three phases: the first (I) selective (also
known as ferromagnetic) phase, the second (II) intermediate phase
with some residual order, and the third (III) completely randomized
(also known as paramagnetic) phase."
"We calculate the phase diagram for these phases and the concentration
of information carriers in the master sequence (also known as peak
configuration) x(0) and other classes of information carriers. As
the phase point moves across the boundary between phase I and phase
II, x(0) changes continuously; as the phase point moves across the
boundary between phase II and phase III, x(0) has a large change,"
wrote D.B. Saakian and colleagues (see also Physics).
The researchers concluded: "Our results are applicable for the general
case of a fitness landscape."
Saakian and colleagues published the results of their research in
Physical Review E (Phase diagram for the Eigen quasispecies theory
with a truncated fitness landscape. Physical Review E, 2009;79(4
Part 1):1905).
For additional information, contact D.B. Saakian, Yerevan Physics
Institute, Alikhanian Bros St. 2, Yerevan 375036, Armenia.
The publisher of the journal Physical Review E can be contacted
at: American Physical Society, One Physics Ellipse, College Pk,
MD 20740-3844, USA.
Science Letter
June 16, 2009
According to a study from Yerevan, Armenia, "Using methods of
statistical physics, we present rigorous theoretical calculations
of Eigen's quasispecies theory with the truncated fitness landscape
which dramatically limits the available sequence space of information
carriers. As the mutation rate is increased from small values to large
values, one can observe three phases: the first (I) selective (also
known as ferromagnetic) phase, the second (II) intermediate phase
with some residual order, and the third (III) completely randomized
(also known as paramagnetic) phase."
"We calculate the phase diagram for these phases and the concentration
of information carriers in the master sequence (also known as peak
configuration) x(0) and other classes of information carriers. As
the phase point moves across the boundary between phase I and phase
II, x(0) changes continuously; as the phase point moves across the
boundary between phase II and phase III, x(0) has a large change,"
wrote D.B. Saakian and colleagues (see also Physics).
The researchers concluded: "Our results are applicable for the general
case of a fitness landscape."
Saakian and colleagues published the results of their research in
Physical Review E (Phase diagram for the Eigen quasispecies theory
with a truncated fitness landscape. Physical Review E, 2009;79(4
Part 1):1905).
For additional information, contact D.B. Saakian, Yerevan Physics
Institute, Alikhanian Bros St. 2, Yerevan 375036, Armenia.
The publisher of the journal Physical Review E can be contacted
at: American Physical Society, One Physics Ellipse, College Pk,
MD 20740-3844, USA.